sofosbuvir
Sign in to saveSofosbuvir, sold under the brand name Sovaldi among others, is a medication used to treat hepatitis C. It is taken by mouth.
Article
31 sectionsContents
- Medical uses
- Initial HCV treatment
- Prior failed treatment
- Pregnancy and breastfeeding
- Contraindications
- Side effects
- Interactions
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Chemistry
- History
- Society and culture
- Economics
- United States
- Japan and South Korea
- Germany
- Switzerland
- United Kingdom
- Croatia
- India
- Developing world
- Controversies
- Patent challenges
- Medical tourism
- Research
- DIY Home Synthesis
- See also
- References
- Further reading
- External links
Sofosbuvir, sold under the brand name Sovaldi among others, is a medication used to treat hepatitis C. It is taken by mouth.
Common side effects include fatigue, headache, nausea, and trouble sleeping. Side effects are generally more common in interferon-containing regimens. Sofosbuvir may reactivate hepatitis B in those who have been previously infected. In combination with ledipasvir, daclatasvir or simeprevir, it is not recommended with amiodarone due to the risk of an abnormally slow heartbeat. Sofosbuvir is in the nucleotide analog family of medications and works by blocking the hepatitis C NS5B protein.