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GeneQ18031730· pop 5· linked from 488 articles

Also known as SRIF-2, SS-1-R, SS1-R, SS1R, Somatostatin receptor 1

protein-coding gene in the species Homo sapiens

Gene data

SSTR1
Name
somatostatin receptor 1
Type
protein-coding
Aliases
SRIF-2, SS-1-R, SS1-R, SS1R, SST1

Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. The protein encoded by this gene is a member of the superfamily of somatostatin receptors having seven transmembrane segments. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This somatostatin receptor has greater affinity for somatostatin-14 than -28. [provided by RefSeq, Jul 2012].

via MyGene.info

Wikidata facts

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HomoloGene ID
820
genomic end
38682272
genomic start
38207904
cytogenetic location
14q21.1
Sources (6)

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