SSTR1
Sign in to saveAlso known as SRIF-2, SS-1-R, SS1-R, SS1R, Somatostatin receptor 1
protein-coding gene in the species Homo sapiens
Gene data
SSTR1- Name
- somatostatin receptor 1
- Type
- protein-coding
- Position
- 38,207,895–38,213,067 (+)
- Aliases
- SRIF-2, SS-1-R, SS1-R, SS1R, SST1
- Ensembl
- ENSG00000139874
- RefSeq RNA
- NM_001049.3, XM_047431728.1, XM_054376648.1
- RefSeq protein
- NP_001040.1, XP_047287684.1, XP_054232623.1
Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. The protein encoded by this gene is a member of the superfamily of somatostatin receptors having seven transmembrane segments. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This somatostatin receptor has greater affinity for somatostatin-14 than -28. [provided by RefSeq, Jul 2012].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
somatostatin receptor 1
- Symbol
- SSTR1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:38,207,895-38,213,067
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 820
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6751
- genomic end
- 38682272
- genomic start
- 38207904
- chromosome
- human chromosome 14
- cytogenetic location
- 14q21.1
- expressed in
- dorsolateral prefrontal cortex
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