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EntityQ3790542· pop 15· linked from 188 articles

sulfinpyrazone

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Also known as ANR315, Anturane®, Apo-sulfinpyrazone®, G 28315, NSC 75925, suphinpyrazone, Sulfoxyphenylpyrazolidine, 4-(2-Benzenesulfinylethyl)-1,2-diphenylpyrazolidine-3,5-dione

Sulfinpyrazone is a uricosuric medication used to treat gout. It also sometimes is used to reduce platelet aggregation by inhibiting degranulation of platelets which reduces the release of ADP and thromboxane.

Wikidata facts

Mass
404.119464
Has use
medication
Show 7 more facts
chemical formula
C₂₃H₂₀N₂O₃S
World Health Organisation international non-proprietary name
sulfinpyrazone
medical condition treated
angina pectoris
canonical SMILES
C1=CC=C(C=C1)N2C(=O)C(C(=O)N2C3=CC=CC=C3)CCS(=O)C4=CC=CC=C4
defined daily dose
0.3
physically interacts with
Solute carrier family 22 member 12
Commons category
Sulfinpyrazone
Sources (5)

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Encyclopedic overview

3 sections
Contents
  • Contraindications
  • Research
  • References

Sulfinpyrazone is a uricosuric medication used to treat gout. It also sometimes is used to reduce platelet aggregation by inhibiting degranulation of platelets which reduces the release of ADP and thromboxane.

Like other uricosurics, sulfinpyrazone works by competitively inhibiting uric acid reabsorption in the proximal tubule of the kidney.

Excerpted from Wikipedia’s “sulfinpyrazone” article, available under the CC BY-SA 4.0 licence.