Structure via PubChem · Public domain (PubChem)
talipexole
Sign in to saveAlso known as B-HT920, BHT920
Talipexole (B-HT920, Domnin) is a dopamine agonist that is marketed as a treatment for Parkinson's disease in Japan by Boehringer Ingelheim; it was introduced in 1996. As of December 2014 it was not approved for marketing in the US nor in Europe.
Chemical data
- Formula
- C10H15N3S
- Molecular weight
- 209.31 g/mol
- IUPAC name
- 6-prop-2-enyl-4,5,7,8-tetrahydro-[1,3]thiazolo[4,5-d]azepin-2-amine
- SMILES
- C=CCN1CCC2=C(CC1)SC(=N2)N
- InChIKey
- DHSSDEDRBUKTQY-UHFFFAOYSA-N
- XLogP
- 1.5
- Polar surface area
- 70.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 209.098668
Show 4 more facts
- Commons category
- Talipexole
- chemical formula
- C₁₀H₁₅N₃S
- subject has role
- antidepressant
- canonical SMILES
- C=CCN1CCC2=C(CC1)SC(=N2)N
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
Talipexole (B-HT920, Domnin) is a dopamine agonist that is marketed as a treatment for Parkinson's disease in Japan by Boehringer Ingelheim; it was introduced in 1996. As of December 2014 it was not approved for marketing in the US nor in Europe.
Talipexole is a dopamine D2 receptor agonist and interacts with both pre- and post-synaptic receptors. It also is an α2-adrenergic agonist.
Excerpted from Wikipedia’s “talipexole” article, available under the CC BY-SA 4.0 licence.