Structure via PubChem · Public domain (PubChem)
talsupram
Sign in to saveTalsupram (Lu 5-005 or Lu 5-003) is a selective norepinephrine reuptake inhibitor (NRI) which was investigated as an antidepressant in the 1960s and 1970s but was never marketed. Along with talopram, it is structurally related to the selective serotonin reuptake inhibitor (SSRI) citalopram.
Chemical data
- Formula
- C20H25NS
- Molecular weight
- 311.5 g/mol
- IUPAC name
- 3-(3,3-dimethyl-1-phenyl-2-benzothiophen-1-yl)-N-methylpropan-1-amine
- SMILES
- CC1(C2=CC=CC=C2C(S1)(CCCNC)C3=CC=CC=C3)C
- InChIKey
- FKHYYOUFMJBLAF-UHFFFAOYSA-N
- XLogP
- 4.3
- Polar surface area
- 37.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 311.170771
Show 3 more facts
- chemical formula
- C₂₀H₂₅NS
- canonical SMILES
- CC1(C2=CC=CC=C2C(S1)(CCCNC)C3=CC=CC=C3)C
- Commons category
- Talsupram
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Talsupram (Lu 5-005 or Lu 5-003) is a selective norepinephrine reuptake inhibitor (NRI) which was investigated as an antidepressant in the 1960s and 1970s but was never marketed. Along with talopram, it is structurally related to the selective serotonin reuptake inhibitor (SSRI) citalopram.
== See also == Talopram
Excerpted from Wikipedia’s “talsupram” article, available under the CC BY-SA 4.0 licence.