thioacetamide

Also known as Thioactamide, TAA, Thioacetimidic acid, Thiacetamide, Acetothioamide, methylthioamide, acetic acid thioamide, ethanethioamide

Thioacetamide is an organosulfur compound with the formula C2H5NS. This white crystalline solid is soluble in water and serves as a source of sulfide ions in the synthesis of organic and inorganic compounds. It is a prototypical thioamide.

In the Vinony graph

Within Vinony's link graph, thioacetamide is referenced by 14 other articles, and connects out to carcinogen, hydrogen and carbon.

It sits within the topics Chembox having GHS data, Chembox image size set and ECHA InfoCard ID from Wikidata.

Its subject is documented across 22 Wikipedia language editions.

Chemical data

Formula: C2H5NS
Molecular weight: 75.14 g/mol
IUPAC name: ethanethioamide
SMILES: CC(=S)N
InChIKey: YUKQRDCYNOVPGJ-UHFFFAOYSA-N
XLogP: -0.3
Polar surface area: 58.1 Å²
H-bond donors: 1
H-bond acceptors: 1
Formal charge: 0

via PubChem

Drug data · ChEMBL

Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 75.014

Show 5 more facts

chemical formula: C₂H₅NS
canonical SMILES: CC(=S)N
melting point: 112
Commons category: Thioacetamide
subject has role: carcinogen

Sources (4)

via Wikidata · CC0

~2 min read

Encyclopedic overview

6 sections

Contents

Research
Coordination chemistry
Preparation
Structure
Safety
References

==Research== Thioacetamide is known to induce acute or chronic liver disease (fibrosis and cirrhosis) in the experimental animal model. Its administration in rat induces hepatic encephalopathy, metabolic acidosis, increased levels of transaminases, abnormal coagulation, and centrilobular necrosis, which are the main features of the clinical chronic liver disease so thioacetamide can precisely replicate the initiation and progression of human liver disease in an experimental animal model.

Excerpted from Wikipedia’s “thioacetamide” article, available under the CC BY-SA 4.0 licence.