TNFAIP8

Also known as GG2-1, MDC-3.13, NDED, SCC-S2, SCCS2, TNF alpha induced protein 8

Tumor necrosis factor, alpha-induced protein 8 is a protein that in humans is encoded by the TNFAIP8 gene. It is preferentially expressed in human immune cell types.

In the Vinony graph

Vinony's link graph records 3 inbound references to TNFAIP8, and connects out to PubMed, human chromosome 5 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 5.

Vinony links it to 6 Wikipedia language editions.

Gene data

TNFAIP8

Name: TNF alpha induced protein 8
Type: protein-coding
Position: 119,268,691–119,399,688 (+)
Aliases: GG2-1, MDC-3.13, NDED, SCC-S2, SCCS2
Ensembl: ENSG00000145779
RefSeq RNA: NM_001077654.3, NM_001286813.2, NM_001286814.1, NM_001286815.2, NM_001286817.2
RefSeq protein: NP_001071122.1, NP_001273742.1, NP_001273743.1, NP_001273744.1, NP_001273746.1

Enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in positive regulation of apoptotic process. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

regulation of apoptotic process positive regulation of apoptotic process negative regulation of apoptotic process regulation of intracellular signal transduction

Molecular function

protein binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process cysteine-type endopeptidase inhibitor activity involved in apoptotic process

Cellular component

nucleoplasm cytoplasm cytoplasm cytoplasm

Pathways

Metabolism PI Metabolism Phospholipid metabolism Metabolism of lipids

via MyGene.info

Gene · Ensembl

TNF alpha induced protein 8

Symbol: TNFAIP8
Biotype: Protein coding
Organism: Homo sapiens
Location: 5:119,268,691-119,399,688
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 8649
exact match: identifiers.org/ncbigene/25816
found in taxon: Homo sapiens
chromosome: human chromosome 5
genomic start: 118604387
genomic end: 118735383
cytogenetic location: 5q23.1
expressed in: trabecular bone

Sources (4)

via Wikidata · CC0

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Encyclopedic overview

2 sections

Contents

References
Further reading

Tumor necrosis factor, alpha-induced protein 8 is a protein that in humans is encoded by the TNFAIP8 gene. It is preferentially expressed in human immune cell types.

==References==

Excerpted from Wikipedia’s “TNFAIP8” article, available under the CC BY-SA 4.0 licence.