tolperisone
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Tolperisone (trade name Mydocalm among others) is a centrally acting skeletal muscle relaxant used for the treatment of increased muscle tone associated with neurological diseases. It has been used since the 1960s.
Research
218 papers- Tolperisone induces UPR-mediated tumor inhibition and synergizes with proteasome inhibitor and immunotherapy by targeting LSD1.Expert opinion on therapeutic targets · 2023
- Pregabalin-Tolperisone Combination to Treat Neuropathic Pain: Improved Analgesia and Reduced Side Effects in Rats.Pharmaceuticals (Basel, Switzerland) · 2023
- Tolperisone: a typical representative of a class of centrally acting muscle relaxants with less sedative side effects.CNS neuroscience & therapeutics · 2008
- Effects of CYP2D6*10 allele on the pharmacokinetics of tolperisone.Archives of pharmacal research · 2023
- Tolperisone for the Treatment of Acute Muscle Spasm of the Back: Results from the Dose-Ranging Phase 2 STAR Study (NCT03802565).Journal of pain research · 2020
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Encyclopedic overview
13 sectionsContents
- Medical uses
- Contraindications and cautions
- Side effects
- Overdose
- Interactions
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Chemistry
- Society and culture
- Brand names
- See also
- References
Tolperisone (trade name Mydocalm among others) is a centrally acting skeletal muscle relaxant used for the treatment of increased muscle tone associated with neurological diseases. It has been used since the 1960s.
== Medical uses == Tolperisone is indicated for use in the treatment of pathologically increased tone of the skeletal muscle caused by neurological diseases (damage of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis) and of spastic paralysis and other encephalopathies manifested with muscular dystonia.
Excerpted from Wikipedia’s “tolperisone” article, available under the CC BY-SA 4.0 licence.