Structure via PubChem · Public domain (PubChem)
triaziquone
Sign in to saveAlso known as 2,3,5-Tri(1-aziridinyl)-p-benzoquinone, 2,3,5-Ethylenimine-1,4-benzoquinone, 2,3,5-Triethyleneimino-1,4-benzoquinone, Tris(ethyleneimino)benzoquinone, 2,3,5-Tris(1-aziridino)-p-benzoquinone, 2,3,5-Tri-(1-aziridinyl)-p-benzoquinone, 2,3,5-Trisethyleneiminobenzoquinone, 2,3,5-Tris(aziridino)-1,4-benzoquinone
Triaziquone is a drug used in chemotherapy.
Chemical data
- Formula
- C12H13N3O2
- Molecular weight
- 231.25 g/mol
- IUPAC name
- 2,3,5-tris(aziridin-1-yl)cyclohexa-2,5-diene-1,4-dione
- SMILES
- C1CN1C2=CC(=O)C(=C(C2=O)N3CC3)N4CC4
- InChIKey
- PXSOHRWMIRDKMP-UHFFFAOYSA-N
- XLogP
- -0.1
- Polar surface area
- 43.2 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- neoplasm
via ChEMBL · EBI
Research
518 papers- Synthesis and antitumor evaluation of novel bis-triaziquone derivatives.Molecules (Basel, Switzerland) · 2009
- A study on inhibition mechanism of breast cancer cells by bis-type triaziquone.European journal of pharmacology · 2010
- Comparisons of the chemical and biologic properties of triaziquone and triaziquone-protein conjugates.Journal of the National Cancer Institute · 1978
- A sequential screening of the cytogenetic damage induced by triaziquone.Mutation research · 1978
- Chromosome aberrations in metaphase II oocytes of Chinese hamster (Cricetulus griseus). I. The sensitivity of the pre-ovulatory phase to triaziquone.Mutation research · 1974
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 231.101
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₂H₁₃N₃O₂
- canonical SMILES
- C1CN1C2=CC(=O)C(=C(C2=O)N3CC3)N4CC4
- World Health Organisation international non-proprietary name
- triaziquone
- subject has role
- carcinogen
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Triaziquone is a drug used in chemotherapy.
It is aziridinylbenzoquinone-based, and may have potential antineoplastic activity.
Excerpted from Wikipedia’s “triaziquone” article, available under the CC BY-SA 4.0 licence.
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