UBA5

Also known as THIFP1, UBE1DC1, ubiquitin like modifier activating enzyme 5, SCAR24, EIEE44, DEE44

Ubiquitin-like modifier-activating enzyme 5 is a protein that in humans is encoded by the UBA5 gene.

In the Vinony graph

Within Vinony's link graph, UBA5 is referenced by 109 other articles, and connects out to PubMed, human chromosome 3 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 3.

Its subject is documented across 6 Wikipedia language editions.

Gene data

UBA5

Name: ubiquitin like modifier activating enzyme 5
Type: protein-coding
Position: 132,654,446–132,679,794 (+)
Aliases: DEE44, EIEE44, SCAR24, THIFP1, UBE1DC1
Ensembl: ENSG00000081307
RefSeq RNA: NM_001320210.2, NM_001321238.2, NM_001321239.1, NM_024818.6, NM_198329.4
RefSeq protein: NP_001307139.1, NP_001308167.1, NP_001308168.1, NP_079094.1, NP_938143.1

This gene encodes a member of the E1-like ubiquitin-activating enzyme family. This protein activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been identified on chromosome 1. [provided by RefSeq, Feb 2016].

Pathways

Adaptive Immune System Disease Immune System Infectious disease Viral Infection Pathways Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Dengue Virus Infection Dengue Virus Attachment and Entry

via MyGene.info

Gene · Ensembl

ubiquitin like modifier activating enzyme 5

Symbol: UBA5
Biotype: Protein coding
Organism: Homo sapiens
Location: 3:132,654,446-132,679,794
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein UBA5 PDB 3GUC.png

Show 7 more facts

HomoloGene ID: 11738
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/79876
genomic end: 132679794
genomic start: 132373290
chromosome: human chromosome 3
cytogenetic location: 3q22.1

Sources (4)

via Wikidata · CC0

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Encyclopedic overview

3 sections

Contents

References
Further reading
External links

Ubiquitin-like modifier-activating enzyme 5 is a protein that in humans is encoded by the UBA5 gene.

This gene encodes a member of the E1-like activating enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Excerpted from Wikipedia’s “UBA5” article, available under the CC BY-SA 4.0 licence.