UBA5

Also known as THIFP1, UBE1DC1, ubiquitin like modifier activating enzyme 5, SCAR24, EIEE44, DEE44

Ubiquitin-like modifier-activating enzyme 5 is a protein that in humans is encoded by the UBA5 gene.

Gene data

UBA5

Name: ubiquitin like modifier activating enzyme 5
Type: protein-coding
Position: 132,654,446–132,679,794 (+)
Aliases: DEE44, EIEE44, SCAR24, THIFP1, UBE1DC1
Ensembl: ENSG00000081307
RefSeq RNA: NM_001320210.2, NM_001321238.2, NM_001321239.1, NM_024818.6, NM_198329.4
RefSeq protein: NP_001307139.1, NP_001308167.1, NP_001308168.1, NP_079094.1, NP_938143.1

This gene encodes a member of the E1-like ubiquitin-activating enzyme family. This protein activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been identified on chromosome 1. [provided by RefSeq, Feb 2016].

Pathways

Adaptive Immune System Disease Immune System Infectious disease Viral Infection Pathways Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Dengue Virus Infection Dengue Virus Attachment and Entry

via MyGene.info

Wikidata facts

Image: Protein UBA5 PDB 3GUC.png

Show 5 more facts

HomoloGene ID: 11738
exact match: identifiers.org/ncbigene/79876
genomic end: 132679794
genomic start: 132373290
cytogenetic location: 3q22.1

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Ubiquitin-like modifier-activating enzyme 5 is a protein that in humans is encoded by the UBA5 gene.

This gene encodes a member of the E1-like activating enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.