UBE2L6
Sign in to saveAlso known as RIG-B, UBCH8, ubiquitin conjugating enzyme E2 L6
Ubiquitin/ISG15-conjugating enzyme E2 L6 is a protein that in humans is encoded by the UBE2L6 gene.
In the Vinony graph
Vinony's link graph records 107 inbound references to UBE2L6, and connects out to PubMed, human chromosome 11 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 11.
Vinony links it to 6 Wikipedia language editions.
Gene data
UBE2L6- Name
- ubiquitin conjugating enzyme E2 L6
- Type
- protein-coding
- Position
- 57,551,656–57,568,284 (−)
- Aliases
- RIG-B, UBCH8
- Ensembl
- ENSG00000156587
- RefSeq RNA
- NM_004223.5, NM_198183.3
- RefSeq protein
- NP_004214.1, NP_937826.1
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2011].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
ubiquitin conjugating enzyme E2 L6
- Symbol
- UBE2L6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:57,551,656-57,568,284
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein UBE2L6 PDB 1wzv.png
Show 7 more facts
- HomoloGene ID
- 3112
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9246
- genomic end
- 57335757
- genomic start
- 57319129
- chromosome
- human chromosome 11
- cytogenetic location
- 11q12.1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Ubiquitin/ISG15-conjugating enzyme E2 L6 is a protein that in humans is encoded by the UBE2L6 gene.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family.
Excerpted from Wikipedia’s “UBE2L6” article, available under the CC BY-SA 4.0 licence.