UBL5
Sign in to saveAlso known as HUB1, ubiquitin like 5
Ubiquitin-like protein 5 is a protein that in humans is encoded by the UBL5 gene.
Gene data
UBL5- Name
- ubiquitin like 5
- Type
- protein-coding
- Position
- 9,827,892–9,830,137 (+)
- Aliases
- HUB1
- Ensembl
- ENSG00000198258
- RefSeq RNA
- NM_001048241.3, NM_024292.4, XM_054321656.1
- RefSeq protein
- NP_001041706.1, NP_077268.1, XP_054177631.1
This gene encodes a member of a group of proteins similar to ubiquitin. The encoded protein is not thought to degrade proteins like ubiquitin but to affect their function through being bound to target proteins by an isopeptide bond. The gene product has been studied as a link to predisposition to obesity based on its expression in Psammomys obesus, the fat sand rat, which is an animal model for obesity studies. Variation in this gene was found to be significantly associated with some metabolic traits (PMID: 15331561) but not associated with childhood obesity (PMID: 19189687). Pseudogenes of this gene are located on chromosomes 3, 5 and 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2013].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Wikidata facts
- Image
- Protein UBL5 PDB 1p0r.png
Show 5 more facts
- HomoloGene ID
- 83305
- exact match
- identifiers.org/ncbigene/59286
- genomic start
- 9938568
- genomic end
- 9940791
- cytogenetic location
- 19p13.2
Sources (3)
via Wikidata · CC0
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Article
3 sectionsContents
- References
- Further reading
- External links
Ubiquitin-like protein 5 is a protein that in humans is encoded by the UBL5 gene.
It has been shown that in C. elegans mitochondria treated to lower expression of certain electron transport chain proteins during the L3/L4 stage, its expression levels is higher leading to increased lifespans.