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cloprednol

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EntityQ3680915· pop 8· linked from 272 articles

cloprednol

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Cloprednol is a synthetic glucocorticoid. It has been investigated for use in asthma.

Chemical data

Formula
C21H25ClO5
Molecular weight
392.9 g/mol
IUPAC name
(9S,10R,11S,13S,14S,17R)-6-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one
SMILES
C[C@]12C[C@@H]([C@H]3C([C@@H]1CC[C@@]2(C(=O)CO)O)C=C(C4=CC(=O)C=C[C@]34C)Cl)O
InChIKey
YTJIBEDMAQUYSZ-YNAZYXNTSA-N
XLogP
1.9
Polar surface area
94.8 Ų
H-bond donors
3
H-bond acceptors
5
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
392.13905157999994
Show 5 more facts
chemical formula
C₂₁H₂₅ClO₅
isomeric SMILES
C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)C=C(C4=CC(=O)C=C[C@]34C)Cl)O
NCI Thesaurus ID
C80809
Commons category
Cloprednol
canonical SMILES
CC12C=CC(=O)C=C1C(Cl)=CC1C2C(O)CC2(C)C1CCC2(O)C(=O)CO
Sources (2)

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Encyclopedic overview

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Contents
  • References

Cloprednol is a synthetic glucocorticoid. It has been investigated for use in asthma.

==References==

Excerpted from Wikipedia’s “cloprednol” article, available under the CC BY-SA 4.0 licence.

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