YAP1
Sign in to saveAlso known as COB1, YAP, YAP2, YAP65, YKI, Yes associated protein 1, Yap, Yes1 associated transcriptional regulator
gene umano
Gene data
YAP1- Name
- Yes1 associated transcriptional regulator
- Type
- protein-coding
- Position
- 102,109,968–102,233,534 (+)
- Aliases
- COB1, YAP, YAP-1, YAP2, YAP65, YKI
- Ensembl
- ENSG00000137693
- RefSeq RNA
- NM_001130145.3, NM_001195044.2, NM_001195045.2, NM_001282097.2, NM_001282098.2
- RefSeq protein
- NP_001123617.1, NP_001181973.1, NP_001181974.1, NP_001269026.1, NP_001269027.1
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
Yes1 associated transcriptional regulator
- Symbol
- YAP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:102,109,968-102,233,534
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein YAP1 PDB 1jmq.png
Show 7 more facts
- HomoloGene ID
- 4452
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10413
- genomic end
- 102233424
- genomic start
- 102110447
- chromosome
- human chromosome 11
- cytogenetic location
- 11q22.1
via Wikidata · CC0