YAP1
Sign in to saveAlso known as COB1, YAP, YAP2, YAP65, YKI, Yes associated protein 1, Yap, Yes1 associated transcriptional regulator
gen van de soort Homo sapiens
In the Vinony graph
Vinony's link graph records 50 inbound references to YAP1, and connects out to PubMed, transcription factor and carcinogenesis.
Vinony files it under Genes on human chromosome 11 and Transcription factors.
Vinony links it to 6 Wikipedia language editions.
Gene data
YAP1- Name
- Yes1 associated transcriptional regulator
- Type
- protein-coding
- Position
- 102,109,968–102,233,534 (+)
- Aliases
- COB1, YAP, YAP-1, YAP2, YAP65, YKI
- Ensembl
- ENSG00000137693
- RefSeq RNA
- NM_001130145.3, NM_001195044.2, NM_001195045.2, NM_001282097.2, NM_001282098.2
- RefSeq protein
- NP_001123617.1, NP_001181973.1, NP_001181974.1, NP_001269026.1, NP_001269027.1
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
Yes1 associated transcriptional regulator
- Symbol
- YAP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:102,109,968-102,233,534
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein YAP1 PDB 1jmq.png
Show 7 more facts
- HomoloGene ID
- 4452
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10413
- genomic end
- 102233424
- genomic start
- 102110447
- chromosome
- human chromosome 11
- cytogenetic location
- 11q22.1
via Wikidata · CC0