Forkhead transcription factors

Forkhead box protein P2 (FOXP2) is a protein that, in humans, is encoded by the FOXP2 gene. FOXP2 is a member of the forkhead box family of transcription factors, proteins that regulate gene expression by binding to DNA. It is expressed in the brain, heart, lungs and digestive system.

FOXP3 (forkhead box P3), also known as scurfin, is a protein involved in immune system responses. A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of regulatory T cells. Regulatory T cells generally turn the immune response down. In cancer, an excess of regulatory T cell activity can prevent the immune system from destroying cancer cells. In autoimmune disease, a deficiency of regulatory T cell activity can allow other autoimmune cells to attack the body's own tissues.

Forkhead box protein M1 is a protein that in humans is encoded by the FOXM1 gene. The protein encoded by this gene is a member of the FOX family of transcription factors. Its potential as a target for future cancer treatments led to it being designated the 2010 Molecule of the Year.

Forkhead box O3, also known as FOXO3 or FOXO3a, is a human protein encoded by the FOXO3 gene.

Forkhead box protein O4 is a protein that in humans is encoded by the FOXO4 gene.

Forkhead box protein K1 is a transcription factor of the forkhead box family that in humans is encoded by the FOXK1 gene.

family of transcription factors involved in anatomical development

Forkhead box protein N1 is a protein that in humans is encoded by the FOXN1 gene.

Forkhead box protein E3 (FOXE3) also known as forkhead-related transcription factor 8 (FREAC-8) is a protein that in humans is encoded by the FOXE3 gene located on the short arm of chromosome 1.

protein-coding gene in the species Homo sapiens

Forkhead box protein K2 is a protein that in humans is encoded by the FOXK2 gene.

Forkhead box protein G1 is a protein that in humans is encoded by the FOXG1 gene.

Forkhead box protein N3 is a protein that in humans is encoded by the FOXN3 gene.

Forkhead box I1 is a protein that in humans is encoded by the FOXI1 gene.

Forkhead box Q1 is a protein that in humans is encoded by the FOXQ1 gene.

Forkhead box protein E1 is a protein that in humans is encoded by the FOXE1 gene.

Forkhead box protein P1 is a protein that in humans is encoded by the FOXP1 gene. FOXP1 is necessary for the proper development of the brain, heart, and lung in mammals. It is a member of the large FOX family of transcription factors.

Forkhead box protein J2 is a protein that in humans is encoded by the FOXJ2 gene.

Forkhead box protein A2 (FOXA2), also known as hepatocyte nuclear factor 3-beta (HNF-3B), is a transcription factor that plays an important role during development, in mature tissues and, when dysregulated or mutated, also in cancer.

Forkhead box S1 is a protein that in humans is encoded by the FOXS1 gene.

Forkhead box protein C2 (FOXC2) also known as forkhead-related protein FKHL14 (FKHL14), transcription factor FKH-14, or mesenchyme fork head protein 1 (MFH1) is a protein that in humans is encoded by the FOXC2 gene. FOXC2 is a member of the fork head box (FOX) family of transcription factors.

Forkhead box protein D4 is a protein that in humans is encoded by the FOXD4 gene. ==References==

Forkhead box protein H1 is a protein that in humans is encoded by the FOXH1 gene.

Forkhead box protein P4 is a protein that in humans is encoded by the FOXP4 gene.

Forkhead box protein F1 (FOXF1) is a protein that in humans is encoded by the FOXF1 gene.