Human proteins

A disintegrin and metalloprotease 17 (ADAM17), also called TACE (tumor necrosis factor-α-converting enzyme), is a 70-kDa enzyme that belongs to the ADAM protein family of disintegrins and metalloproteases, activated by substrate presentation.

Myotilin is a protein that in humans is encoded by the MYOT gene. Myotilin (myofibrillar titin-like protein) also known as TTID (TiTin Immunoglobulin Domain) is a muscle protein that is found within the Z-disc of sarcomeres.

Kinesin-like protein KIF2A is a protein that in humans is encoded by the KIF2A gene. In mice, KIF2A is essential for proper neurogenesis and deficiency of KIF2A in mature neurons results in the loss of those neurons.

Dpy-19-like 2 (C. elegans) is a protein that in humans is encoded by the DPY19L2 gene.

Diphosphoinositol pentakisphosphate kinase 2 is a protein that in humans is encoded by the PPIP5K2 gene.

Seizure threshold 2 homolog is a protein that in humans is encoded by the SZT2 gene.

BUB3-interacting and GLEBS motif-containing protein ZNF207 is a protein in humans that is encoded by the ZNF207 gene.

Unc-93 homolog A (C. elegans) is a protein that in humans is encoded by the UNC93A gene.

Marginal zone B and B1 cell-specific protein is a protein that in humans is encoded by the MZB1 gene.

Kinesin-like protein KIF1A, also known as axonal transporter of synaptic vesicles or microtubule-based motor KIF1A, is a protein that in humans is encoded by the KIF1A gene.

Storkhead box 1 is a protein in humans that is encoded by the STOX1 gene.

Inverted formin-2 is a protein that in humans is encoded by the INF2 gene. It belongs to the protein family called the formins. It has two splice isoforms, CAAX which localizes to the endoplasmic reticulum and non-CAAX which localizes to focal adhesions and the cytoplasm with enrichment at the Golgi. INF2 plays a role in mitochondrial fission and dorsal stress fiber formation. INF2 accelerates actin nucleation and elongation by interacting with barbed ends (fast-growing ends) of actin filaments, but also accelerates disassembly of actin through encircling and severing filaments.

BPI fold-containing family B member 1 (BPIFB1) is a protein that in humans is encoded by the BPIFB1 gene. BPIFB1 is a secreted protein, expressed at very high levels in mucosa of the airways (respiratory and olfactory epithelium) and salivary glands, and at moderate levels in the digestive tract (tongue, stomach, intestinal epithelium) and pancreas.

Neuroblastoma breakpoint family, member 15, also known as NBPF15, is a protein which in humans is encoded by the NBPF15 gene. The gene is 18762 bp long, with mRNA that is 3837 bp long. The gene is located on chromosome 1q21.1. Its sub-cellular location is predicted to be in the nucleus and cytoplasm. It contains what is known as the NBPF repeat, which is a two-exon stretch of sequence that is characteristic of all 21 members of the NBPF gene family. The repeat is considered the ancestral exons, and the NBPF family has been linked to primate evolution.

Lysine demethylase 8 is a protein that in humans is encoded by the KDM8 gene.

Family with sequence similarity 181, member A is a protein that in humans is encoded by the FAM181A gene.

Fatty acid binding protein 9, testis is a protein that in humans is encoded by the FABP9 gene.

Transmembrane protein 215 is a protein that in humans is encoded by the TMEM215 gene.

Tetratricopeptide repeat domain 28 is a protein that in humans is encoded by the TTC28 gene.

Delta(4)-desaturase, sphingolipid 2 is a protein that in humans is encoded by the DEGS2 gene.

Ribosomal oxygenase 1 is a protein that in humans is encoded by the RIOX1 gene (previously NO66). The protein is involved in ribosome biogenesis and replication and regulation of heterochromatic regions of the nucleus. It is a chromatin regulator, and a regulator of osteoblast differentiation. It is a Jumonji C (JmjC) domain-containing protein in the subgroup of ribosomal oxygenases (ROXs), part of the superfamily of Fe(II) and 2-oxoglutarate (2OG) dependent oxygenases. Ribosomal oxygenase 1 It is a dual-location protein found in the nucleus, nucleolus, and nucleoplasm of the cell. RIOX1 is a

Nucleosome assembly protein 1-like 1 is a protein that in humans is encoded by the NAP1L1 gene.

ADP-ribosylation factor 6 (ARF6) is a member of the ADP ribosylation factor family of GTP-binding proteins. ARF6 has a variety of cellular functions that are frequently involved in trafficking of biological membranes and transmembrane protein cargo. ARF6 has specifically been implicated in endocytosis of plasma membrane proteins and also, to a lesser extent, plasma membrane protein recycling.

Fanconi anemia, complementation group I (FANCI) also known as KIAA1794, is a protein which in humans is encoded by the FANCI gene. Mutations in the FANCI gene are known to cause Fanconi anemia.

Nuclear factor of activated T-cells, cytoplasmic 1 is a protein that in humans is encoded by the NFATC1 gene.

Activin receptor type-2B is a protein that in humans is encoded by the ACVR2B gene. ACVR2B is an activin type 2 receptor.

NGFI-A-binding protein 2 also known as EGR-1-binding protein 2 or melanoma-associated delayed early response protein (MADER) is a protein that in humans is encoded by the NAB2 gene.

Sprouty-related, EVH1 domain-containing protein 2 is a protein that in humans is encoded by the SPRED2 gene.

Beta-soluble NSF attachment protein is a SNAP protein involved in vesicular trafficking and exocytosis which is encoded by the NAPB gene humans is.

Acrosomal protein SP-10 is a protein that in humans is encoded by the ACRV1 gene.

CKLF-like MARVEL transmembrane domain-containing protein 2 (i.e. CMTM2), previously termed chemokine-like factor superfamily 2 ( i.e. CKLFSF2), is a member of the CKLF-like MARVEL transmembrane domain-containing family (CMTM) of proteins. In humans, it is encoded by the CMTM2 gene located in band 22 on the long (i.e. "q") arm of chromosome 16. CMTM2 protein is expressed in the bone marrow and various circulating blood cells. It is also highly expressed in testicular tissues: The CMTM2 gene and CMTM2 protein, it is suggested, may play an important role in testicular development.

Neuroblastoma breakpoint family member 10 is a protein that in Homo sapiens is encoded by the NBPF10 gene.

Solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 is a protein that in humans is encoded by the SLC8B1 gene.

RNA binding motif protein 47 is a protein in humans that is encoded by the RBM47 gene in chromosome 4.

Protein phosphatase 1, regulatory subunit 27 is a protein in humans that is encoded by the PPP1R27 gene.

Lysine demethylase 6B is a protein that in humans is encoded by the KDM6B (JMJD3) gene.

Lysine demethylase 7A is a protein that in humans is encoded by the KDM7A gene.

Lactamase, beta 2 is a protein that in humans is encoded by the LACTB2 gene.

FAST kinase domain-containing protein 3 (FASTKD3) is a protein that in humans is encoded by the FASTKD3 gene on chromosome 5. This protein is part of the Fas-activated serine/threonine kinase domain (FASTKD) containing protein family, which is known for regulating the energy balance of mitochondria under stress.

Eva-1 homolog A (C. elegans) is a protein that in humans is encoded by the EVA1A gene.

Solute carrier family 46 member 3 (SLC46A3) is a protein that in humans is encoded by the SLC46A3 gene. Also referred to as FKSG16, the protein belongs to the major facilitator superfamily (MFS) and SLC46A family. Most commonly found in the plasma membrane and endoplasmic reticulum (ER), SLC46A3 is a multi-pass membrane protein with 11 α-helical transmembrane domains. It is mainly involved in the transport of small molecules across the membrane through the substrate translocation pores featured in the MFS domain. The protein is associated with breast and prostate cancer, hepatocellular carcino

Cyclic GMP-AMP synthase is a protein that in humans is encoded by the CGAS gene. It's an enzyme, a nucleotidyltransferase, a cyclic GMP-AMP synthase. == References ==

Fructose-1,6-bisphosphatase 1 is a protein that in humans is encoded by the FBP1 gene.

HMG-box containing 3 is a protein that in humans is encoded by the HMGXB3 gene.

Glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) is a protein in humans that is encoded by the GRINA gene.

In cell biology, CTDNEP1 (CTD nuclear envelope phosphatase 1) is a protein coding gene involved in neural development. It is a member of DXDX(T/V) phosphatase family and is a potential regulator of neural tube development in Xenopus. The gene promotes neural development by inhibiting bone morphogenetic proteins (BMPs). The encoded protein is relatively small and only contains 244 amino acids.

Myogenin, is a transcriptional activator encoded by the MYOG gene. Myogenin is a muscle-specific basic-helix-loop-helix (bHLH) transcription factor involved in the coordination of skeletal muscle development or myogenesis and repair. Myogenin is a myogenic regulatory factor (MRF), other examples of which also include MyoD, Myf5, and MRF4.

Histone H4-like protein type G is a protein that in humans is encoded by the HIST1H4G gene.

Condensin complex subunit 3 also known as condensin subunit CAP-G (CAP-G) or non-SMC condensin I complex subunit G (NCAPG) is a protein that in humans is encoded by the NCAPG gene. CAP-G is a subunit of condensin I, a large protein complex involved in chromosome condensation.

Norrin, also known as Norrie disease protein or X-linked exudative vitreoretinopathy 2 protein (EVR2) is a protein that in humans is encoded by the NDP gene. Mutations in the NDP gene are associated with the Norrie disease.

APOBEC1 complementation factor is a protein that in humans is encoded by the A1CF gene.

Condensin-2 complex subunit G2 (CAP-G2) also known as chromosome-associated protein G2 (CAP-G2) or leucine zipper protein 5 (LUZP5) is a protein that in humans is encoded by the NCAPG2 gene. CAP-G2 is a subunit of condensin II, a large protein complex involved in chromosome condensation. It interacts with PLK1 through its C-terminal region during mitosis

Amelogenin, X isoform is a protein that in humans is encoded by the AMELX gene. AMELX is located on the X chromosome and encodes a set of isoforms of amelogenin by alternative splicing. Amelogenin is an extracellular matrix protein involved in the process of amelogenesis, the formation of enamel on teeth.

Condensin complex subunit 1 also known as chromosome-associated protein D2 (CAP-D2) or non-SMC condensin I complex subunit D2 (NCAPD2) or XCAP-D2 homolog is a protein that in humans is encoded by the NCAPD2 gene. CAP-D2 is a subunit of condensin I, a large protein complex involved in chromosome condensation.

Pappalysin-1, also known as pregnancy-associated plasma protein A, and insulin-like growth factor binding protein-4 protease is a protein encoded by the PAPPA gene in humans. PAPPA is a secreted protease whose main substrate is insulin-like growth factor binding proteins. Pappalysin-1 is also used in screening tests for Down syndrome.

E3 ubiquitin-protein ligase NEDD4, also known as neural precursor cell expressed developmentally down-regulated protein 4 (whence "NEDD4") is an enzyme that is, in humans, encoded by the NEDD4 gene.

Natural cytotoxicity triggering receptor 1 is a protein that in humans is encoded by the NCR1 gene. NCR1 has also been designated as CD335 (cluster of differentiation nomenclature), NKP46, NKp46, NK-p46, and LY94.

Kinesin family member KIF18A is a human protein encoded by the KIF18A gene. It is part of the kinesin family of motor proteins.

Neogenin is a protein that in humans is encoded by the NEO1 gene.

Elongation factor RNA polymerase II-like 3 is a protein that in humans is encoded by the ELL3 gene.