2-chlorodiazepam
Diclazepam (Ro5-3448), also known as chlorodiazepam and '''2'-chloro-diazepam''', is a benzodiazepine and functional analog of diazepam. It was first synthesized by Leo Sternbach and his team at Hoffman-La Roche in 1960. It is not currently approved for use as a medication, but rather sold as an unscheduled substance. Efficacy and safety have not been tested in humans.
Chemical data
- Formula
- C16H12Cl2N2O
- Molecular weight
- 319.2 g/mol
- IUPAC name
- 7-chloro-5-(2-chlorophenyl)-1-methyl-3H-1,4-benzodiazepin-2-one
via PubChem
Research
13 papers- Overdose from designer benzodiazepine Diclazepam.QJM : monthly journal of the Association of Physicians · 2020
- Designer benzodiazepines versus prescription benzodiazepines: can structural relation predict the next step?Critical reviews in toxicology · 2021
- Discriminative stimulus and reinforcing effects of diclazepam in rodents.Pharmacology, biochemistry, and behavior · 2024
- Organ distribution of diclazepam, pyrazolam and 3-fluorophenmetrazine.Forensic science international · 2019
- Highly Efficient Dual-Color Luminophores for Sensitive and Selective Detection of Diclazepam Based on MOF/COF Bi-Mesoporous Composites.
Article
6 sectionsContents
- Metabolism
- Legal status
- United Kingdom
- United States
- See also
- References
Diclazepam (Ro5-3448), also known as chlorodiazepam and '''2'-chloro-diazepam', is a benzodiazepine and functional analog of diazepam. It was first synthesized by Leo Sternbach and his team at Hoffman-La Roche in 1960. It is not currently approved for use as a medication, but rather sold as an unscheduled substance. Efficacy and safety have not been tested in humans.
In animal models, its effects are similar to diazepam, possessing long-acting anxiolytic, anticonvulsant, hypnotic, sedative, skeletal muscle relaxant, and amnestic properties.