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2-heptylamine

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EntityQ4000097· pop 7· linked from 1,571 articles

2-heptylamine

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Also known as tuamine, 1-methylhexylamine, 2-heptanamine, 2-aminoheptane

Tuaminoheptane (, ; brand names Heptin, Heptadrine, Tuamine; also known as tuamine and 2-aminoheptane) is a sympathomimetic agent and vasoconstrictor which is used as a nasal decongestant. It has also been used as a stimulant.

Chemical data

Formula
C7H17N
Molecular weight
115.22 g/mol
IUPAC name
heptan-2-amine
SMILES
CCCCCC(C)N
InChIKey
VSRBKQFNFZQRBM-UHFFFAOYSA-N
XLogP
2.4
Polar surface area
26 Ų
H-bond donors
1
H-bond acceptors
1
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule
Indications
Nasal congestion

via ChEMBL · EBI

Wikidata facts

Mass
115.136
Show 3 more facts
chemical formula
C₇H₁₇N
canonical SMILES
CCCCCC(C)N
Commons category
2-Heptylamine
Sources (2)

via Wikidata · CC0

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Encyclopedic overview

3 sections
Contents
  • See also
  • References
  • External links

Tuaminoheptane (, ; brand names Heptin, Heptadrine, Tuamine; also known as tuamine and 2-aminoheptane) is a sympathomimetic agent and vasoconstrictor which is used as a nasal decongestant. It has also been used as a stimulant.

Tuaminoheptane has been found to act as a reuptake inhibitor and releasing agent of norepinephrine, which may underlie its decongestant and stimulant effects. It is an alkylamine. The chemical structure of the drug differs from that of other norepinephrine releasing agents, such as the phenethylamines, which, in contrast to tuaminoheptane, have an aromatic ring in their structure.

Excerpted from Wikipedia’s “2-heptylamine” article, available under the CC BY-SA 4.0 licence.

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