ACTA2

Name

actin alpha 2, smooth muscle

Type

protein-coding

Position

88,934,815–88,991,339 (−)

Aliases

ACTSA, SMDYS

Ensembl

ENSG00000107796

RefSeq RNA

NM_001141945.3, NM_001320855.2, NM_001406462.1, NM_001406463.1, NM_001406464.1

RefSeq protein

NP_001135417.1, NP_001307784.1, NP_001393391.1, NP_001393392.1, NP_001393393.1

This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017].

via MyGene.info

Gene · Ensembl

actin alpha 2, smooth muscle

Symbol

ACTA2

Biotype

Protein coding

Organism

Homo sapiens

Location

10:88,934,815-88,991,339

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein ACTA2 PDB 1atn.png

via Wikidata · CC0