AP2A2
Sign in to saveAlso known as ADTAB, CLAPA2, HIP-9, HIP9, HYPJ, adaptor related protein complex 2 alpha 2 subunit, adaptor related protein complex 2 subunit alpha 2
gene umano
In the Vinony graph
Within Vinony's link graph, AP2A2 is referenced by 85 other articles, and connects out to PubMed, human chromosome 11 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 11.
Its subject is documented across 7 Wikipedia language editions.
Gene data
AP2A2- Name
- adaptor related protein complex 2 subunit alpha 2
- Type
- protein-coding
- Position
- 924,881–1,012,245 (+)
- Aliases
- ADTAB, CLAPA2, HIP-9, HIP9, HYPJ
- Ensembl
- ENSG00000281385
- RefSeq RNA
- NM_001242837.2, NM_012305.4, NR_144509.2, NR_144510.2, XM_011519929.2
- RefSeq protein
- NP_001229766.1, NP_036437.1, XP_011518231.1, XP_011518232.1, XP_047282435.1
The protein encoded by this gene is a subunit of the AP-2 adaptor protein complex, which is involved in linking lipid and protein membrane components with the clathrin lattice. This interaction supports the formation of clathrin-coated vesicles, and the encoded subunit aids in the process by binding polyphosphoinositide-containing lipids in the cell membrane. [provided by RefSeq, Nov 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
adaptor related protein complex 2 subunit alpha 2
- Symbol
- AP2A2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HSCHR11_3_CTG1:3,478-81,830
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein AP2A2 PDB 1b9k.png
Show 9 more facts
- HomoloGene ID
- 5335
- found in taxon
- Homo sapiens
- genetic association
- Alzheimer's disease
- exact match
- identifiers.org/ncbigene/161
- chromosome
- human chromosome 11
- genomic start
- 924881
- genomic end
- 1012239
- cytogenetic location
- 11p15.5
- expressed in
- ganglionic eminence
via Wikidata · CC0