CLSTN1
Sign in to saveAlso known as ALC-ALPHA, CDHR12, CSTN1, PIK3CD, XB31alpha, alcalpha1, alcalpha2, CST-1
Calsyntenin-1 is a protein that in humans is encoded by the CLSTN1 gene.
In the Vinony graph
Vinony's link graph records 5 inbound references to CLSTN1, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 1.
Vinony links it to 7 Wikipedia language editions.
Gene data
CLSTN1- Name
- calsyntenin 1
- Type
- protein-coding
- Position
- 9,728,911–9,823,993 (−)
- Aliases
- ALC-ALPHA, CDHR12, CST-1, CSTN1, XB31alpha, alcalpha1, alcalpha2
- Ensembl
- ENSG00000171603
- RefSeq RNA
- NM_001009566.3, NM_001302883.1, NM_014944.4, XM_047449470.1, XM_054335191.1
- RefSeq protein
- NP_001009566.1, NP_001289812.1, NP_055759.3, XP_047305426.1, XP_054191166.1
This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
calsyntenin 1
- Symbol
- CLSTN1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:9,728,911-9,823,993
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- found in taxon
- Homo sapiens
- HomoloGene ID
- 8814
- exact match
- identifiers.org/ncbigene/22883
- genomic end
- 9823984
- genomic start
- 9728926
- chromosome
- human chromosome 1
- cytogenetic location
- 1p36.22
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Clinical relevance
- Interactions
- References
- External links
- Further reading
Calsyntenin-1 is a protein that in humans is encoded by the CLSTN1 gene.
== Clinical relevance ==
Excerpted from Wikipedia’s “CLSTN1” article, available under the CC BY-SA 4.0 licence.
Available in 7 languages
via Wikidata sitelinks · CC0