CLSTN1
Sign in to saveAlso known as ALC-ALPHA, CDHR12, CSTN1, PIK3CD, XB31alpha, alcalpha1, alcalpha2, CST-1
Calsyntenin-1 is a protein that in humans is encoded by the CLSTN1 gene.
Gene data
CLSTN1- Name
- calsyntenin 1
- Type
- protein-coding
- Aliases
- ALC-ALPHA, CDHR12, CST-1, CSTN1, XB31alpha, alcalpha1, alcalpha2
This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014].
via MyGene.info
Gene · Ensembl
calsyntenin 1
- Symbol
- CLSTN1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:9,728,911-9,823,993
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 8814
- exact match
- identifiers.org/ncbigene/22883
- genomic end
- 9823984
- genomic start
- 9728926
- cytogenetic location
- 1p36.22
Sources (4)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Clinical relevance
- Interactions
- References
- External links
- Further reading
Calsyntenin-1 is a protein that in humans is encoded by the CLSTN1 gene.
== Clinical relevance ==
Available in 7 languages
via Wikidata sitelinks · CC0