AQP3
Sign in to saveAlso known as AQP-3, GIL, aquaporin 3 (Gill blood group)
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In the Vinony graph
Vinony's link graph records 395 inbound references to AQP3, and connects out to PubMed, Ensembl genome database project and water.
Vinony files it under Blood antigen systems, Blood proteins and Genes on human chromosome 9.
Vinony links it to 9 Wikipedia language editions.
Gene data
AQP3- Name
- aquaporin 3 (Gill blood group)
- Type
- protein-coding
- Aliases
- AQP-3, GIL
This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015].
via MyGene.info
Gene · Ensembl
aquaporin 3 (Gill blood group)
- Symbol
- AQP3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:33,441,156-33,447,596
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 21025
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/360
- genomic end
- 33447596
- genomic start
- 33441156
- chromosome
- human chromosome 9
- cytogenetic location
- 9p13.3
- expressed in
- nipple
via Wikidata · CC0
~2 min read
Encyclopedic overview
5 sectionsContents
- Clinical significance
- See also
- References
- Further reading
- External links
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Aquaporin 3 (AQP-3) is the protein product of the human AQP3 gene. It is found in the basolateral cell membrane of principal collecting duct cells and provides a pathway for water to exit these cells. Aquaporin-3 is also permeable to glycerol, ammonia, urea, and hydrogen peroxide. It is expressed in various tissues including the skin, respiratory tract, and kidneys as well as various types of cancers. In the kidney, aquaporin-3 is unresponsive to the antidiuretic hormone vasopressin, unlike aquaporin-2. This protein is also a determinant for the GIL blood group system.
Excerpted from Wikipedia’s “AQP3” article, available under the CC BY-SA 4.0 licence.