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avizafone

Structure via PubChem · Public domain (PubChem)

EntityQ4829057· pop 8· linked from 540 articles

Also known as LDZ

Avizafone (Pro-Diazepam) is a water-soluble prodrug of the benzodiazepine derivative diazepam. It can be administered intramuscularly.

In the Vinony graph

Within Vinony's link graph, avizafone is referenced by 540 other articles, and connects out to benzodiazepine drug, intramuscular injection and alphenal.

Vinony files it under 2-Aminobenzophenones, Antidotes and Benzodiazepine prodrugs.

Its subject is documented across 8 Wikipedia language editions.

Chemical data

Formula
C22H27ClN4O3
Molecular weight
430.9 g/mol
IUPAC name
(2S)-2,6-diamino-N-[2-(2-benzoyl-4-chloro-N-methylanilino)-2-oxoethyl]hexanamide
SMILES
CN(C1=C(C=C(C=C1)Cl)C(=O)C2=CC=CC=C2)C(=O)CNC(=O)[C@H](CCCCN)N
InChIKey
LTKOVYBBGBGKTA-SFHVURJKSA-N
XLogP
1.9
Polar surface area
119 Ų
H-bond donors
3
H-bond acceptors
5
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
430.177
Show 3 more facts
isomeric SMILES
CN(C1=C(C=C(C=C1)Cl)C(=O)C2=CC=CC=C2)C(=O)CNC(=O)[C@H](CCCCN)N
canonical SMILES
CN(C1=C(C=C(C=C1)Cl)C(=O)C2=CC=CC=C2)C(=O)CNC(=O)C(CCCCN)N
chemical formula
C₂₂H₂₇ClN₄O₃
Sources (2)

via Wikidata · CC0

~2 min read

Encyclopedic overview

2 sections
Contents
  • See also
  • References

{{Drugbox | Verifiedfields = changed | verifiedrevid = 444777910 | IUPAC_name = (2S)-2,6-diamino-N-{[(2-benzoyl-4-chlorophenyl)methylcarbamoyl]methyl}hexanamide | image = Avizafone.svg | image_class = skin-invert-image | width = 240

| tradename = | legal_status = | routes_of_administration = Intramuscular injection

Excerpted from Wikipedia’s “avizafone” article, available under the CC BY-SA 4.0 licence.

Available in 8 languages

via Wikidata sitelinks · CC0

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