BIRC2
Sign in to saveAlso known as API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1, baculoviral IAP repeat containing 2
Genen från arten Homo sapiens
In the Vinony graph
Vinony's link graph records 43 inbound references to BIRC2, and connects out to PubMed, Ensembl genome database project and cancer.
It sits within the topics Genes on human chromosome 11, Microbiology and Oncology.
Vinony links it to 6 Wikipedia language editions.
Gene data
BIRC2- Name
- baculoviral IAP repeat containing 2
- Type
- protein-coding
- Position
- 102,347,208–102,378,680 (+)
- Aliases
- API1, HIAP2, Hiap-2, IAP-2, MIHB, RNF48, c-IAP1, cIAP1
- Ensembl
- ENSG00000110330
- RefSeq RNA
- NM_001166.5, NM_001256163.1, NM_001256166.2, XM_054368611.1, XM_054368612.1
- RefSeq protein
- NP_001157.1, NP_001243092.1, NP_001243095.1, XP_054224586.1, XP_054224587.1
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
baculoviral IAP repeat containing 2
- Symbol
- BIRC2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:102,347,208-102,378,680
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein BIRC2 PDB 1qbh.png
Show 7 more facts
- HomoloGene ID
- 900
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/329
- genomic end
- 102249401
- genomic start
- 102217942
- chromosome
- human chromosome 11
- cytogenetic location
- 11q22.2
Sources (3)
via Wikidata · CC0