In the Vinony graph
Vinony's link graph records 157 inbound references to BMP2, and connects out to activin and inhibin, BMP7 and PubMed.
It is catalogued under topics including Bone morphogenetic protein, Developmental genes and proteins and Genes on human chromosome 20.
Vinony links it to 10 Wikipedia language editions.
Gene data
BMP2- Name
- bone morphogenetic protein 2
- Type
- protein-coding
- Position
- 6,767,679–6,782,614 (+)
- Aliases
- BDA2, BMP2A, SSFSC, SSFSC1
- Ensembl
- ENSG00000125845
- RefSeq RNA
- NM_001200.4
- RefSeq protein
- NP_001191.1
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
bone morphogenetic protein 2
- Symbol
- BMP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:6,767,679-6,782,614
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- BMP2.png
Show 9 more facts
- HomoloGene ID
- 926
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/650
- genomic end
- 6780246
- genomic start
- 6767686
- chromosome
- human chromosome 20
- cytogenetic location
- 20p12.3
- Commons category
- Bone morphogenetic protein-2 (BMP-2)
- expressed in
- glomerulus
via Wikidata · CC0
Available in 10 languages
via Wikidata sitelinks · CC0