Structure via PubChem · Public domain (PubChem)
برومفناک
Sign in to saveAlso known as AHR-10282B, 2-amino-3-(4-bromobenzoyl)benzeneacetic acid, [2-amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid
داروی ضدالتهاب چشم
Chemical data
- Formula
- C15H12BrNO3
- Molecular weight
- 334.16 g/mol
- IUPAC name
- 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
- SMILES
- C1=CC(=C(C(=C1)C(=O)C2=CC=C(C=C2)Br)N)CC(=O)O
- InChIKey
- ZBPLOVFIXSTCRZ-UHFFFAOYSA-N
- XLogP
- 3.3
- Polar surface area
- 80.4 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1997
- Admin. routes
- topical
- Indications
- eye inflammation, inflammation, allergic conjunctivitis, dry eye syndrome
via ChEMBL · EBI
Research
325 papers- Bromfenac.2006
- Topical bromfenac in VEGF-driven maculopathies: topical review and meta-analysis.BMC ophthalmology · 2024
- Topical bromfenac for prevention and treatment of cystoid macular edema following cataract surgery: a review.Clinical ophthalmology (Auckland, N.Z.) · 2016
- Role of microsomal metabolism in bromfenac-induced cytotoxicity.Chemico-biological interactions · 2024
- Bromfenac Ophthalmic Solution 0.07%: A Review of Its Use After Cataract Surgery.Clinical drug investigation · 2015
via PubMed
Wikidata facts
- Subclass of
- non-steroidal anti-inflammatory drug
- Mass
- 333
- Has use
- medication
Show 7 more facts
- chemical formula
- C₁₅H₁₂BrNO₃
- subject has role
- non-steroidal anti-inflammatory drug
- medical condition treated
- pain
- canonical SMILES
- C1=CC(=C(C(=C1)CC(=O)O)N)C(=O)C2=CC=C(C=C2)Br
- World Health Organisation international non-proprietary name
- bromfenac
- physically interacts with
- Prostaglandin-endoperoxide synthase 2
- Commons category
- Bromfenac
via Wikidata · CC0