bufexamac
Sign in to saveBufexamac is a drug used as an anti-inflammatory agent on the skin, as well as rectally. Common brand names include Paraderm and Parfenac. It was withdrawn in Europe and Australia because of allergic reactions.
Key facts
- Drug.H
- 17
- Drug.N
- 1
- Drug.O
- 3
- Drug.IUPAC_name
- 2-(4-butoxyphenyl)-N-hydroxyacetamide
- Drug.image
- Bufexamac Structural Formula V2.svg
- Drug.image_class
- skin-invert-image
- Drug.legal_status
- OTC
- Drug.routes_of_administration
- Topical, rectal
- Drug.excretion
- Renal
- Drug.IUPHAR_ligand
- 7498
- Drug.CAS_number
- 2438-72-4
- Drug.ATC_prefix
- M01
- Drug.ATC_suffix
- AB17
- Drug.PubChem
- 2466
- Drug.ChEMBL
- 94394
- Drug.ChemSpiderID
- 2372
- Drug.UNII
- 4T3C38J78L
- Drug.KEGG
- D01271
via Wikipedia infobox
Chemical data
- Formula
- C12H17NO3
- Molecular weight
- 223.27 g/mol
- IUPAC name
- 2-(4-butoxyphenyl)-N-hydroxyacetamide
via PubChem
Article
4 sectionsContents
- Indications
- Pharmacology
- Side effects
- References
Bufexamac is a drug used as an anti-inflammatory agent on the skin, as well as rectally. Common brand names include Paraderm and Parfenac. It was withdrawn in Europe and Australia because of allergic reactions.
==Indications== Ointments and lotions containing bufexamac are used for the treatment of subacute and chronic eczema of the skin, including atopic eczema, as well as sunburn and other minor burns, and itching. Suppositories containing bufexamac in combination with local anaesthetics are used against haemorrhoids.