Structure via PubChem · Public domain (PubChem)
butamben
Sign in to saveAlso known as BAB, butyl aminobenzoate, butyl p-aminobenzoate, p-aminobenzoic acid butyl ester, 4-aminobenzoic acid butyl ester, n-butyl p-aminobenzoate, 4-(butoxycarbonyl)aniline
Butamben is a local anesthetic. Proprietary names includes Alvogil in Spain and Alvogyl in Switzerland. It is one of three components in the topical anesthetic Cetacaine.
Chemical data
- Formula
- C11H15NO2
- Molecular weight
- 193.24 g/mol
- IUPAC name
- butyl 4-aminobenzoate
- SMILES
- CCCCOC(=O)C1=CC=C(C=C1)N
- InChIKey
- IUWVALYLNVXWKX-UHFFFAOYSA-N
- XLogP
- 2.9
- Polar surface area
- 52.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
67 papers- Lipid nanoparticles loaded with butamben and designed to improve anesthesia at inflamed tissues.Biomaterials science · 2021
- Improvement of Butamben Anesthetic Efficacy by the Development of Deformable Liposomes Bearing the Drug as Cyclodextrin Complex.Pharmaceutics · 2021
- Analgesic synergy between topical morphine and butamben in mice.Anesthesia and analgesia · 2003
- Inhibition of sensory neuronal TRPs contributes to anti-nociception by butamben.Neuroscience letters · 2012
- Butamben derivatives enhance BMP-2-stimulated commitment of C2C12 cells into osteoblasts with induction of voltage-gated potassium channel expression.Bioorganic & medicinal chemistry letters · 2011
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 193.11
Show 4 more facts
- chemical formula
- C₁₁H₁₅NO₂
- canonical SMILES
- CCCCOC(=O)C1=CC=C(C=C1)N
- melting point
- 57.5
- subject has role
- local anesthetic
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Chemistry
- Synthesis
- References
Butamben is a local anesthetic. Proprietary names includes Alvogil in Spain and Alvogyl in Switzerland. It is one of three components in the topical anesthetic Cetacaine.
== Chemistry ==
Excerpted from Wikipedia’s “butamben” article, available under the CC BY-SA 4.0 licence.
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via Wikidata sitelinks · CC0