Structure via PubChem · Public domain (PubChem)
captodiame
Sign in to saveAlso known as 2-[(4-butylsulfanylphenyl)-phenyl-methyl]sulfanyl-N,N-dimethylethanamine, captodiamine
Captodiame (INN), also known as captodiamine, is an antihistamine sold under the trade names Covatine, Covatix, and Suvren which is used as a sedative and anxiolytic. The structure is related to diphenhydramine.
Chemical data
- Formula
- C21H29NS2
- Molecular weight
- 359.6 g/mol
- IUPAC name
- 2-[(4-butylsulfanylphenyl)-phenylmethyl]sulfanyl-N,N-dimethylethanamine
- SMILES
- CCCCSC1=CC=C(C=C1)C(C2=CC=CC=C2)SCCN(C)C
- InChIKey
- IZLPZXSZLLELBJ-UHFFFAOYSA-N
- XLogP
- 5.9
- Polar surface area
- 53.8 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- anxiety
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 359.174
- Has use
- medication
Show 3 more facts
- chemical formula
- C₂₁H₂₉NS₂
- canonical SMILES
- CCCCSC1=CC=C(C=C1)C(C2=CC=CC=C2)SCCN(C)C
- defined daily dose
- 0.2
Sources (3)
via Wikidata · CC0
~2 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
Captodiame (INN), also known as captodiamine, is an antihistamine sold under the trade names Covatine, Covatix, and Suvren which is used as a sedative and anxiolytic. The structure is related to diphenhydramine.
A 2004 study suggested captodiame may be helpful in preventing benzodiazepine withdrawal syndrome in people discontinuing benzodiazepine treatment.
Excerpted from Wikipedia’s “captodiame” article, available under the CC BY-SA 4.0 licence.
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via Wikidata sitelinks · CC0