Structure via PubChem · Public domain (PubChem)
کارباکول
Sign in to saveAlso known as CAR405, 2-(carbamoyloxy)-N,N,N-trimethylethanaminium, (2-hydroxyethyl)trimethylammonium chloride carbamate, (2-hydroxyethyl)trimethyl ammonium chloride carbamate, 2-[(aminocarbonyl)oxy]-N,N,N-trimethylethanaminum chloride, carbamylcholine, choline chlorine carbamate, 2-[(aminocarbonyl)oxy]-N,N,N-trimethylethanaminium chloride
Carbachol, also known as carbamylcholine and sold under the brand name Miostat among others, is a cholinomimetic drug that binds and activates acetylcholine receptors. Thus it is classified as a cholinergic agonist. It is primarily used for various ophthalmic purposes, such as for treating glaucoma, or for use during ophthalmic surgery. It is generally administered as an ophthalmic solution (i.e., eye drops).
Chemical data
- Formula
- C6H15ClN2O2
- Molecular weight
- 182.65 g/mol
- IUPAC name
- 2-carbamoyloxyethyl(trimethyl)azanium chloride
- SMILES
- C[N+](C)(C)CCOC(=O)N.[Cl-]
- InChIKey
- AIXAANGOTKPUOY-UHFFFAOYSA-N
- Polar surface area
- 52.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1972
- Admin. routes
- parenteral
- Indications
- presbyopia, Miosis, cataract, glaucoma
via ChEMBL · EBI
Research
19,551 papers- Carbachol dose response.American journal of ophthalmology · 1989
- Local carbachol application induces oral microvascular recruitment and improves gastric tissue oxygenation during hemorrhagic shock in dogs.Frontiers in immunology · 2024
- CARBACHOL AND VITAMIN B12 ABSORPTION.British medical journal · 1965
- Carbachol-induced sustained tonic contraction of rat detrusor muscle.BJU international · 1999
- Carbachol in cataract surgery.Archives of ophthalmology (Chicago, Ill. : 1960) · 1968
via PubMed
Wikidata facts
- Subclass of
- carbamate
- Mass
- 182.082
- Has use
- medication
Show 6 more facts
- defined daily dose
- 0.4
- chemical formula
- C₆H₁₅ClN₂O₂
- Commons category
- Carbachol
- World Health Organisation international non-proprietary name
- carbachol
- medical condition treated
- glaucoma
- canonical SMILES
- C[N+](C)(C)CCOC(=O)N.[Cl-]
via Wikidata · CC0