Structure via PubChem · Public domain (PubChem)
carbostyril
Sign in to saveAlso known as 2(1H)-quinolinone, 2-quinolinone, 2-OXOQUINOLINE, 2-quinolone
2-Quinolone is an organic compound related structurally to quinoline. It is the majority tautomer in equilibrium with 2-quinolinol. The compound can be classified as a cyclic amide, and as such is used as an isostere for peptides and other pharmaceutically inspired targets. The 4-methyl-2-quinolone can be prepared by dehydration of acetoacetanilide.
Chemical data
- Formula
- C9H7NO
- Molecular weight
- 145.16 g/mol
- IUPAC name
- 1H-quinolin-2-one
- SMILES
- C1=CC=C2C(=C1)C=CC(=O)N2
- InChIKey
- LISFMEBWQUVKPJ-UHFFFAOYSA-N
- XLogP
- 1.3
- Polar surface area
- 29.1 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 145.053
Show 5 more facts
- chemical formula
- C₉H₇NO
- canonical SMILES
- C1=CC=C2C(=C1)C=CC(=O)N2
- melting point
- 198.0
- found in taxon
- Houttuynia cordata
- Commons category
- 2-Quinolone
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- External links
2-Quinolone is an organic compound related structurally to quinoline. It is the majority tautomer in equilibrium with 2-quinolinol. The compound can be classified as a cyclic amide, and as such is used as an isostere for peptides and other pharmaceutically inspired targets. The 4-methyl-2-quinolone can be prepared by dehydration of acetoacetanilide.
thumb|left|2-Quinolone (right) and its tautomer 2-hydroxyquinoline (left)
Excerpted from Wikipedia’s “carbostyril” article, available under the CC BY-SA 4.0 licence.