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flucindole

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flucindole

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Flucindole (, ; developmental code name WIN-35150) is an antipsychotic of the tetrahydrocarbazolamine family with a tricyclic cyclized tryptamine structure that was never marketed. It is the 6,8-difluoro derivative of ciclindole. The drug is about 5 to 10times more potent than ciclindole both in vitro and in vivo.

Chemical data

Formula
C14H16F2N2
Molecular weight
250.29 g/mol
IUPAC name
6,8-difluoro-N,N-dimethyl-2,3,4,9-tetrahydro-1H-carbazol-3-amine
SMILES
CN(C)C1CCC2=C(C1)C3=C(N2)C(=CC(=C3)F)F
InChIKey
FXNCRITWFOVSEP-UHFFFAOYSA-N
XLogP
3
Polar surface area
19 Ų
H-bond donors
1
H-bond acceptors
3
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
250.128
Show 3 more facts
chemical formula
C₁₄H₁₆F₂N₂
canonical SMILES
CN(C)C1CCC2=C(C1)C3=CC(=CC(=C3N2)F)F
Commons category
Flucindole
Sources (2)

via Wikidata · CC0

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Encyclopedic overview

2 sections
Contents
  • See also
  • References

Flucindole (, ; developmental code name WIN-35150) is an antipsychotic of the tetrahydrocarbazolamine family with a tricyclic cyclized tryptamine structure that was never marketed. It is the 6,8-difluoro derivative of ciclindole. The drug is about 5 to 10times more potent than ciclindole both in vitro and in vivo.

== See also == Tetrahydrocarbazolamine Cyclized tryptamine 5-Fluoro-AMT Iprindole

Excerpted from Wikipedia’s “flucindole” article, available under the CC BY-SA 4.0 licence.

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