CDH2
Sign in to saveAlso known as CD325, CDHN, CDw325, NCAD, cadherin 2, ACOGS, ARVD14
gen de la especie Homo sapiens
Gene data
CDH2- Name
- cadherin 2
- Type
- protein-coding
- Position
- 27,932,879–28,178,024 (−)
- Aliases
- ACOGS, ADHD8, ARVD14, CD325, CDHN, CDw325, NCAD
- Ensembl
- ENSG00000170558
- RefSeq RNA
- NM_001308176.2, NM_001792.5, XM_011525788.1, XM_017025514.3, XM_054318138.1
- RefSeq protein
- NP_001295105.1, NP_001783.2, XP_011524090.1, XP_016881003.1, XP_054174113.1
This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015].
Gene Ontology
Biological process
Molecular function
Pathways
Cell adhesion molecules - Homo sapiens (human)Arrhythmogenic right ventricular cardiomyopathy - Homo sapiens (human)Developmental BiologyDevelopmental BiologyCell-Cell communicationRegulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)Metabolism of proteinsAdherens junctions interactionsCell-cell junction organizationCell junction organization
via MyGene.info
Gene · Ensembl
cadherin 2
- Symbol
- CDH2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 18:27,932,879-28,178,024
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CDH2 PDB 1ncg.png
Show 10 more facts
- HomoloGene ID
- 20424
- genetic association
- obesity
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1000
- genomic end
- 28177946
- genomic start
- 27932879
- chromosome
- human chromosome 18
- cytogenetic location
- 18q12.1
- expressed in
- middle temporal gyrus
- Commons category
- N-cadherin (neural)
via Wikidata · CC0