Cetraxate (INN) is an oral gastrointestinal medication which has a cytoprotective effect.
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Cetraxate (INN) is an oral gastrointestinal medication which has a cytoprotective effect.
==Synthesis== Cetraxate is a prodrug of tranexamic acid. The latter is a hemostatic agent because it inhibits the activation of plasminogen to plasmin. The result is to prevent excess loss of blood in gastrointestinal ulcers. The synthesis begins with the esterification of 3-(p-hydroxyphenyl)propionic acid (2) by trans-4-cyanocyclohexanecarbonyl chloride (1). The product (3) is reduced to cetraxate (4) by catalytic hydrogenation with hydrogen and Raney nickel. thumb|center|700px|class=skin-invert-image|Cetraxate synthesis
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).