ilaprazole

Ilaprazole (trade name Noltec) is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.

Chemical data

Formula: C19H18N4O2S
Molecular weight: 366.4 g/mol
IUPAC name: 2-[(4-methoxy-3-methyl-2-pyridinyl)methylsulfinyl]-6-pyrrol-1-yl-1H-benzimidazole
SMILES: CC1=C(C=CN=C1CS(=O)C2=NC3=C(N2)C=C(C=C3)N4C=CC=C4)OC
InChIKey: HRRXCXABAPSOCP-UHFFFAOYSA-N
XLogP: 2.3
Polar surface area: 92 Å²
H-bond donors: 1
H-bond acceptors: 5
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 3
Molecule type: Small molecule
Indications: duodenal ulcer, gastroesophageal reflux disease, Peptic ulcer, hemorrhage

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 366.115

Show 3 more facts

subject has role: proton-pump inhibitor
chemical formula: C₁₉H₁₈N₄O₂S
canonical SMILES: CC1=C(C=CN=C1CS(=O)C2=NC3=C(N2)C=C(C=C3)N4C=CC=C4)OC

Sources (3)

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Encyclopedic overview

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Contents

References

Ilaprazole (trade name Noltec) is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.

It is available in strengths of 5, 10, and 20 mg.

Excerpted from Wikipedia’s “ilaprazole” article, available under the CC BY-SA 4.0 licence.

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