chloroform
Sign in to saveChloroform, or trichloromethane (often abbreviated as TCM), is an organochloride with the formula and a common solvent. It is a volatile, colorless, sweet-smelling, dense liquid produced on a large scale as a precursor to refrigerants and polytetrafluoroethylene (PTFE). Chloroform was once used as an inhalational anesthetic between the 19th century and the first half of the 20th century. It is miscible with many solvents but it is only very slightly soluble in water (only 8 g/L at 20°C).
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Chloroform is a colorless, sweet-smelling liquid chemical that was historically used as an anesthetic in surgery during the 1800s and early 1900s, but today is primarily produced as a precursor ingredient for making refrigerants and non-stick coatings like PTFE. It remains industrially important because it dissolves easily in many other substances, making it useful as a solvent in chemical manufacturing.
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Article
23 sectionsContents
- Structure and name
- Natural occurrence
- History
- Production
- Deuterochloroform
- Inadvertent formation of chloroform
- Uses
- Solvent
- Refrigerant
- Lewis acid
- Reagent
- Anaesthetic
- Recreational use
- Criminal use
- Safety
- Exposure
- Pharmacology
- Conversion to phosgene
- Regulation
- Bioremediation of chloroform
- Gallery
- References
- External links
Chloroform, or trichloromethane (often abbreviated as TCM), is an organochloride with the formula and a common solvent. It is a volatile, colorless, sweet-smelling, dense liquid produced on a large scale as a precursor to refrigerants and polytetrafluoroethylene (PTFE). Chloroform was once used as an inhalational anesthetic between the 19th century and the first half of the 20th century. It is miscible with many solvents but it is only very slightly soluble in water (only 8 g/L at 20°C).
==Structure and name== The molecule adopts a tetrahedral molecular geometry with C3v symmetry. The chloroform molecule can be viewed as a methane molecule with three hydrogen atoms replaced with three chlorine atoms, leaving a single hydrogen atom.
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5-HT3 receptor positive allosteric modulatorsChembox having GHS dataChembox image size setChemical articles having a data pageChlorine-containing natural productsChloroalkanesChloroformECHA InfoCard ID from WikidataEndocrine disruptorsGABAA receptor positive allosteric modulatorsGlycine receptor agonistsHalogenated solvents