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cyclobendazole

Structure via PubChem · Public domain (PubChem)

EntityQ383730· pop 11· linked from 65 articles

cyclobendazole

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Also known as ciclobendazole

Ciclobendazole is an anthelmintic, that is a pharmaceutical drug against parasitic worms. It underwent a clinical trial in the 1970s, where it was found to be as effective as mebendazole in the treatment of hookworm infection and ascariasis, but significantly less effective in the treatment of trichuriasis.

Chemical data

Formula
C13H13N3O3
Molecular weight
259.26 g/mol
IUPAC name
methyl N-[6-(cyclopropanecarbonyl)-1H-benzimidazol-2-yl]carbamate
SMILES
COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3CC3
InChIKey
OXLKOMYHDYVIDM-UHFFFAOYSA-N
XLogP
1.6
Polar surface area
84.1 Ų
H-bond donors
2
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule
Indications
Helminthiasis

via ChEMBL · EBI

Wikidata facts

Mass
259.096
Show 3 more facts
chemical formula
C₁₃H₁₃N₃O₃
canonical SMILES
COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3CC3
Commons category
Ciclobendazole
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

1 sections
Contents
  • References

Ciclobendazole is an anthelmintic, that is a pharmaceutical drug against parasitic worms. It underwent a clinical trial in the 1970s, where it was found to be as effective as mebendazole in the treatment of hookworm infection and ascariasis, but significantly less effective in the treatment of trichuriasis.

It is not known to be marketed anywhere in the world.

Excerpted from Wikipedia’s “cyclobendazole” article, available under the CC BY-SA 4.0 licence.