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GeneQ17913789· pop 5· linked from 12 articles

Also known as G17P1, HLR1, HUMP68, p68, DEAD-box helicase 5

Probable ATP-dependent RNA helicase DDX5 also known as DEAD box protein 5 or RNA helicase p68 is an enzyme that in humans is encoded by the DDX5 gene.

Gene data

DDX5
Name
DEAD-box helicase 5
Type
protein-coding
Aliases
G17P1, HLR1, HUMP68, p68

This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule, promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2017].

via MyGene.info

Gene · Ensembl

DEAD-box helicase 5

Symbol
DDX5
Biotype
Protein coding
Organism
Homo sapiens
Location
17:64,498,253-64,508,199
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
DEAD BOX 5.png
Show 5 more facts
HomoloGene ID
1655
genomic start
64498254
genomic end
62504317
cytogenetic location
17q23.3
Sources (4)

via Wikidata · CC0

~1 min read

Article

4 sections
Contents
  • Function
  • Interactions
  • References
  • Further reading

Probable ATP-dependent RNA helicase DDX5 also known as DEAD box protein 5 or RNA helicase p68 is an enzyme that in humans is encoded by the DDX5 gene.

== Function ==

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via Wikidata sitelinks · CC0

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