DDX5
Sign in to saveAlso known as G17P1, HLR1, HUMP68, p68, DEAD-box helicase 5
Probable ATP-dependent RNA helicase DDX5 also known as DEAD box protein 5 or RNA helicase p68 is an enzyme that in humans is encoded by the DDX5 gene.
Gene data
DDX5- Name
- DEAD-box helicase 5
- Type
- protein-coding
- Aliases
- G17P1, HLR1, HUMP68, p68
This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule, promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2017].
via MyGene.info
Gene · Ensembl
DEAD-box helicase 5
- Symbol
- DDX5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:64,498,253-64,508,199
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- DEAD BOX 5.png
Show 5 more facts
- HomoloGene ID
- 1655
- exact match
- identifiers.org/ncbigene/1655
- genomic start
- 64498254
- genomic end
- 62504317
- cytogenetic location
- 17q23.3
Sources (4)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Probable ATP-dependent RNA helicase DDX5 also known as DEAD box protein 5 or RNA helicase p68 is an enzyme that in humans is encoded by the DDX5 gene.
== Function ==