DOK5

Also known as C20orf180, IRS-6, IRS6, docking protein 5

Docking protein 5 is a protein that in humans is encoded by the DOK5 gene.

In the Vinony graph

Within Vinony's link graph, DOK5 is referenced by 4 other articles, and connects out to PubMed, human chromosome 20 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 20.

Its subject is documented across 6 Wikipedia language editions.

Gene data

DOK5

Name: docking protein 5
Type: protein-coding
Aliases: C20orf180, IRS-6, IRS6

The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2014].

via MyGene.info