ebastine
Sign in to saveEbastine is a H1 antihistamine with low potential for causing drowsiness.
Key facts
- Drug.verifiedrevid
- 439227374
- Drug.IUPAC_name
- 4-(4-benzhydryloxy-1-piperidyl)-1-(4-tert-butylphenyl)butan-1-one
- Drug.image
- Ebastine.svg
- Drug.image_class
- skin-invert-image
- Drug.caption
- Above: molecular structure of ebastine Below: 3D representation of an ebastine molecule
- Drug.image2
- Ebastine 3D.png
- Drug.image_class2
- bg-transparent
- Drug.routes_of_administration
- Oral
- Drug.protein_bound
- Greater than 95%
- Drug.metabolism
- Hepatic (CYP3A4-mediated), to carebastine
- Drug.elimination_half life
- 15 to 19 hours (carebastine)
- Drug.CAS_number
- 90729-43-4
- Drug.ATC_prefix
- R06
- Drug.ATC_suffix
- AX22
- Drug.PubChem
- 3191
- Drug.ChemSpiderID
- 3079
- Drug.UNII
- TQD7Q784P1
- Drug.ChEMBL
- 305660
via Wikipedia infobox
Article
7 sectionsContents
- Uses
- Safety
- Pharmacokinetic profile
- Brand names
- See also
- References
- External links
Ebastine is a H1 antihistamine with low potential for causing drowsiness.
It does not penetrate the blood–brain barrier to a significant amount and thus combines an effective block of the H1 receptor in peripheral tissue with a low incidence of central side effects, i.e. seldom causing sedation or drowsiness.