equolo

Also known as (S)-(-)-4',7-Isoflavandiol, (-)-Equol, (-)-(S)-Equol, 4',7-Isoflavandiol, (S)-Equol, 4',7-Dihydroxyisoflavan, (S)-3,4-dihydro-3-(4-hydroxyphenyl)-2H-1-Benzopyran-7-ol, S-equol

composto chimico

In the Vinony graph

Vinony's link graph records 664 inbound references to equolo, and connects out to DDT, soybean and soy sauce.

It sits within the topics Chembox image size set, Chemical articles with multiple compound IDs and ECHA InfoCard ID from Wikidata.

Vinony links it to 12 Wikipedia language editions.

Chemical data

Formula: C15H14O3
Molecular weight: 242.27 g/mol
IUPAC name: (3S)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol
SMILES: C1[C@H](COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O
InChIKey: ADFCQWZHKCXPAJ-GFCCVEGCSA-N
XLogP: 3
Polar surface area: 49.7 Å²
H-bond donors: 2
H-bond acceptors: 3
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule
Indications: benign prostatic hyperplasia, breast cancer, Alzheimer disease, chronic kidney disease

via ChEMBL · EBI

Research

1,451 papers

Indole-3-acetic acid alleviates DSS-induced colitis by promoting the production of R-equol from Bifidobacterium pseudolongum.Gut microbes · 2024
Equol and Resveratrol Improve Bone Turnover Biomarkers in Postmenopausal Women: A Clinical Trial.International journal of molecular sciences · 2023
Equol: pharmacokinetics and biological actions.The Journal of nutrition · 2010
Equol: A Bacterial Metabolite from The Daidzein Isoflavone and Its Presumed Beneficial Health Effects.Nutrients · 2019
Equol: history, chemistry, and formation.The Journal of nutrition · 2010

via PubMed

Wikidata facts

Mass: 242.094294

Show 7 more facts

chemical formula: C₁₅H₁₄O₃
canonical SMILES: C1C(COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O
subject has role: phytoestrogen
isomeric SMILES: OC1=CC=C(C=C1)[C@H]2COC3=C(C2)C=CC(O)=C3
NCI Thesaurus ID: C120313
has characteristic: bitterness
found in taxon: pomegranate

Sources (3)

via Wikidata · CC0

Article · Italiano

L'equolo è un composto diidrossifenolico che è stato identificato per la prima volta nel 1932 nell'urina di cavalle gravide (ed è questa l'origine del suo nome) e, solo all'inizio degli anni ottanta, è stato identificato anche nell'urina umana.

Abstract from DBpedia / Wikipedia · CC BY-SA