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ethosuximide
Sign in to saveEthosuximide, sold under the brand name Zarontin among others, is a medication used to treat absence seizures. It may be used by itself or with other antiseizure medications such as valproic acid. Ethosuximide is taken by mouth.
Article
18 sectionsContents
- Medical uses
- Adverse effects
- Central nervous system
- Common
- Rare
- Gastrointestinal
- Genitourinary
- Blood
- Skin
- Eyes
- Drug interactions
- Mechanism of action
- Stereochemistry
- Society and culture
- Cost
- Availability
- See also
- References
Ethosuximide, sold under the brand name Zarontin among others, is a medication used to treat absence seizures. It may be used by itself or with other antiseizure medications such as valproic acid. Ethosuximide is taken by mouth.
Ethosuximide is usually well tolerated. Common side effects include loss of appetite, abdominal pain, diarrhea, and feeling tired. Serious side effects include suicidal thoughts, low blood cell levels, and lupus erythematosus. It is unclear if it has adverse effects on the fetus during pregnancy. Ethosuximide is in the succinimide family of medications. Its mechanism of action is thought to be due to antagonism of the postsynaptic T-type voltage-gated calcium channel.