Structure via PubChem · Public domain (PubChem)
etoperidone
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Etoperidone, associated with several brand names, is an atypical antidepressant which was developed in the 1970s and either is no longer marketed or was never marketed. It is a phenylpiperazine related to trazodone and nefazodone in chemical structure and is a serotonin antagonist and reuptake inhibitor (SARI) similarly to them.
Chemical data
- Formula
- C19H28ClN5O
- Molecular weight
- 377.9 g/mol
- IUPAC name
- 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-4,5-diethyl-1,2,4-triazol-3-one
- SMILES
- CCC1=NN(C(=O)N1CC)CCCN2CCN(CC2)C3=CC(=CC=C3)Cl
- InChIKey
- IZBNNCFOBMGTQX-UHFFFAOYSA-N
- XLogP
- 3
- Polar surface area
- 42.4 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- major depressive disorder
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 377.198238
- Has use
- medication
Show 3 more facts
- chemical formula
- C₁₉H₂₈ClN₅O
- canonical SMILES
- CCC1=NN(C(=O)N1CC)CCCN2CCN(CC2)C3=CC(=CC=C3)Cl
- Commons category
- Etoperidone
Sources (2)
via Wikidata · CC0
~4 min read
Encyclopedic overview
13 sectionsContents
- Medical uses
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- History
- Society and culture
- Generic names
- Brand names
- Research
- See also
- References
- External links
Etoperidone, associated with several brand names, is an atypical antidepressant which was developed in the 1970s and either is no longer marketed or was never marketed. It is a phenylpiperazine related to trazodone and nefazodone in chemical structure and is a serotonin antagonist and reuptake inhibitor (SARI) similarly to them.
==Medical uses== Etoperidone was used or was intended for use as an antidepressant in the treatment of depression.
Excerpted from Wikipedia’s “etoperidone” article, available under the CC BY-SA 4.0 licence.