- Other names
- Thalamic Creutzfeldt-Jakob disease
- Specialty
- Neurology , psychiatry , sleep medicine , neuropathology
- Symptoms
- Progressive insomnia , ataxia , double vision , weight loss , high blood pressure , excessive sweating , fever , agrypnia excitata , panic attacks , dementia , delusions , phobia's , tachycardia , vivid dreams
- Complications
- Permanent state of hypnagogia later in the illness, heart attack
- Usual onset
- 45–50 years old
- Duration
- 18 months (average)
- Types
- Fatal familial insomnia, sporadic fatal insomnia
- Causes
- PrP type 2 ( Genetic mutation (fCJD D178N-129MM/MV), sporadic form (sCJDMM2-T, very rare))
- Risk factors
- Family history
- Diagnostic method
- Suspected based on symptoms, supported by sleep study , PET scan and genetic testing (if familial form is suspected)
- Differential diagnosis