Structure via PubChem · Public domain (PubChem)
فپرازون
Sign in to saveFeprazone (or prenazone) is a drug used for joint and muscular pain.
Chemical data
- Formula
- C20H20N2O2
- Molecular weight
- 320.4 g/mol
- IUPAC name
- 4-(3-methylbut-2-enyl)-1,2-diphenylpyrazolidine-3,5-dione
- SMILES
- CC(=CCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3)C
- InChIKey
- RBBWCVQDXDFISW-UHFFFAOYSA-N
- XLogP
- 3.1
- Polar surface area
- 40.6 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
- Indications
- rheumatic disease, Arthralgia, Myalgia
via ChEMBL · EBI
Research
86 papers- Feprazone Mitigates IL-1β-Induced Cellular Senescence in Chondrocytes.ACS omega · 2021
- Feprazone Ameliorates TNF-α-Induced Loss of Aggrecan via Inhibition of the SOX-4/ADAMTS-5 Signaling Pathway.ACS omega · 2021
- Feprazone Displays Antiadipogenesis and Antiobesity Capacities in in Vitro 3 T3-L1 Cells and in Vivo Mice.ACS omega · 2021
- Feprazone Prevents Free Fatty Acid (FFA)-Induced Endothelial Inflammation by Mitigating the Activation of the TLR4/MyD88/NF-κB Pathway.ACS omega · 2021
- A double-blind trial of feprazone in osteoarthritis of the hip.Current medical research and opinion · 1977
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 320.152
Show 3 more facts
- chemical formula
- C₂₀H₂₀N₂O₂
- canonical SMILES
- CC(=CCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3)C
- subject has role
- non-steroidal anti-inflammatory drug
Sources (2)
via Wikidata · CC0
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via Wikidata sitelinks · CC0