Structure via PubChem · Public domain (PubChem)
Chemical data
- Formula
- C14H10F3NO2
- Molecular weight
- 281.23 g/mol
- IUPAC name
- 2-[3-(trifluoromethyl)anilino]benzoic acid
- SMILES
- C1=CC=C(C(=C1)C(=O)O)NC2=CC=CC(=C2)C(F)(F)F
- InChIKey
- LPEPZBJOKDYZAD-UHFFFAOYSA-N
- XLogP
- 5.2
- Polar surface area
- 49.3 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- rheumatic disease
via ChEMBL · EBI
Research
1,643 papers- Flufenamic acid as an ion channel modulator.Pharmacology & therapeutics · 2013
- Flufenamic acid improves survival and neurologic outcome after successful cardiopulmonary resuscitation in mice.Journal of neuroinflammation · 2022
- Flufenamic acid resensitizes MRSA to gentamicin through synergistic ion modulation.The Journal of antimicrobial chemotherapy · 2026
- Flufenamic acid inhibits osteoclast formation and bone resorption and act against estrogen-dependent bone loss in mice.International immunopharmacology · 2020
- Antibacterial and antibiofilm effects of flufenamic acid against methicillin-resistant Staphylococcus aureus.Pharmacological research · 2020
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 281.066
Show 7 more facts
- chemical formula
- C₁₄H₁₀F₃NO₂
- canonical SMILES
- C1=CC=C(C(=C1)C(=O)O)NC2=CC=CC(=C2)C(F)(F)F
- subject has role
- anti-inflammatory agent
- melting point
- 134
- World Health Organisation international non-proprietary name
- flufenamic acid
- has characteristic
- bitterness
- Commons category
- Flufenamic acid
via Wikidata · CC0