Structure via PubChem · Public domain (PubChem)
fluprednisolone
Sign in to saveAlso known as 6alpha-Fluoro-11beta,17alpha,21-trihydroxypregna-1,4-diene-3,20-dione, 6alpha-Fluoroprednisolone, Fluprednisolonum
Fluprednisolone is a pregnane. It is a corticosteroid.
Chemical data
- Formula
- C21H27FO5
- Molecular weight
- 378.4 g/mol
- IUPAC name
- (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
- SMILES
- C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)C[C@@H](C4=CC(=O)C=C[C@]34C)F)O
- InChIKey
- MYYIMZRZXIQBGI-HVIRSNARSA-N
- XLogP
- 1.4
- Polar surface area
- 94.8 Ų
- H-bond donors
- 3
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1982
- Admin. routes
- oral
via ChEMBL · EBI
Research
330 papers- [Fluprednisolone in the practice of pediatrics].Prensa medica argentina · 1967
- [Fluprednisolone, a corticosteroid of slight diabetogenic effect].Arzneimittel-Forschung · 1970
- Difluprednate for inflammatory eye disorders.Drugs of today (Barcelona, Spain : 1998) · 2011
- [Pseudohyperaldosteronism].Revista clinica espanola · 1984
- Fluprednisolone, a new corticosteroid, in treating allergies.The Journal of new drugs · 1961
via PubMed
Wikidata facts
- Mass
- 378.184
Show 5 more facts
- chemical formula
- C₂₁H₂₇FO₅
- canonical SMILES
- CC12CC(C3C(C1CCC2(C(=O)CO)O)CC(C4=CC(=O)C=CC34C)F)O
- isomeric SMILES
- C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)C[C@@H](C4=CC(=O)C=C[C@]34C)F)O
- subject has role
- glucocorticoid
- Commons category
- Fluprednisolone
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Fluprednisolone is a pregnane. It is a corticosteroid.
==References==
Excerpted from Wikipedia’s “fluprednisolone” article, available under the CC BY-SA 4.0 licence.