Structure via PubChem · Public domain (PubChem)
Фотемустин
Sign in to saveцитостатический лекарственный препарат
Chemical data
- Formula
- C9H19ClN3O5P
- Molecular weight
- 315.69 g/mol
- IUPAC name
- 1-(2-chloroethyl)-3-(1-diethoxyphosphorylethyl)-1-nitrosourea
- SMILES
- CCOP(=O)(C(C)NC(=O)N(CCCl)N=O)OCC
- InChIKey
- YAKWPXVTIGTRJH-UHFFFAOYSA-N
- XLogP
- 0.9
- Polar surface area
- 97.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- neoplasm, glioblastoma multiforme, cutaneous melanoma, melanoma
via ChEMBL · EBI
Research
415 papers- Fotemustine for the treatment of melanoma.Expert opinion on pharmacotherapy · 2011
- Fotemustine in the treatment of brain primary tumors and metastases.Cancer investigation · 1994
- Fotemustine in recurrent high‑grade glioma: MRI neuro‑radiological findings.Oncology letters · 2024
- An overview of fotemustine in high-grade gliomas: from single agent to association with bevacizumab.BioMed research international · 2014
- Focus on Fotemustine.Journal of experimental & clinical cancer research : CR · 2006
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 315.075
- Has use
- medication
Show 4 more facts
- chemical formula
- C₉H₁₉ClN₃O₅P
- canonical SMILES
- CCOP(=O)(C(C)NC(=O)N(CCCl)N=O)OCC
- subject has role
- antineoplastic
- Commons category
- Fotemustine
Sources (2)
via Wikidata · CC0
Article · Русский
Фотемустин — цитостатический противоопухолевый химиотерапевтический лекарственный препарат алкилирующего типа действия. Производное нитрозомочевины.
Abstract from DBpedia / Wikipedia · CC BY-SA
Available in 11 languages
via Wikidata sitelinks · CC0