GABBR2
Sign in to saveAlso known as GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099, gamma-aminobutyric acid type B receptor subunit 2, EIEE59, NDPLHS
Gamma-aminobutyric acid (GABA) B receptor, 2 (GABAB2) is a G-protein coupled receptor subunit encoded by the GABBR2 gene in humans.
Gene data
GABBR2- Name
- gamma-aminobutyric acid type B receptor subunit 2
- Type
- protein-coding
- Aliases
- DEE59, EIEE59, GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099, NDPLHS
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 55902
- exact match
- identifiers.org/ncbigene/9568
- genomic end
- 98708935
- genomic start
- 98288109
- cytogenetic location
- 9q22.33
Sources (4)
via Wikidata · CC0
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Article
6 sectionsContents
- Function
- Interactions
- See also
- References
- Further reading
- External links
Gamma-aminobutyric acid (GABA) B receptor, 2 (GABAB2) is a G-protein coupled receptor subunit encoded by the GABBR2 gene in humans.
== Function ==